Hotels in St. Charles

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Popular hotels in St. Charles

Discover well-known properties in St. Charles that are favoured by visitors more than others. There are 116 hotels in St. Charles and price data was last updated on 13 March 2026. The average price for a hotel in St. Charles is $132/night.
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380 Mulholland Drive, St. Charles, MO, United States
Travel Happy with Drury Hotels. You have enough to worry about while you're traveling. Let us take a few things off your plate, so you can focus on the good stuff. Breakfast, Wi-Fi, dinnertime snacks, soft drinks, popcorn, business center, workout facilities and more - we've got you covered! A microwave and refrigerator can be found in all rooms. Drury Hotels is 100 percent family-owned and operated. At every one of our 150+ locations, you'll consistently experience rooms with crisp sheets, fine linens and cozy surroundings to ensure a good night's sleep.
Pool
Free Wi-Fi
Parking
9.2
Excellent
911 reviews
Location
2.4 km from city centre
1190 South Main Street, St. Charles, MO, United States
Hotel with free parking, 8-minute walk to Ameristar Casino St. Charles Along with an indoor pool, this hotel has a fitness center and concierge services. Free buffet breakfast, free WiFi in public areas, and free self parking are also provided. Additionally, laundry facilities, a 24-hour front desk, and a library are onsite. Country Inn & Suites by Radisson, St. Charles Historic District offers 86 air-conditioned accommodations with coffee/tea makers and hair dryers. Premium satellite television is provided. Refrigerators and microwaves are provided. Bathrooms include shower/tub combinations and complimentary toiletries. This St. Charles hotel provides complimentary wired and wireless Internet access. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Housekeeping is provided daily. Recreational amenities at the hotel include an indoor pool and a fitness center. The recreational activities listed below are available either on site or nearby; fees may apply.
Pool
Free Wi-Fi
Parking
9.0
Excellent
1539 reviews
Location
2.0 km from city centre

Travel insights for hotels in St. Charles

Use these up-to-date, data-driven insights about booking a hotel in St. Charles including ideal times to book, pricing trends, and more.

What is the cheapest month to book a hotel in St. Charles?

The cheapest month to book a hotel in St. Charles is December ($121). Conversely, the most expensive month to stay in St. Charles is September ($149).

What is the cheapest day to stay in a hotel in St. Charles?

The cheapest day to stay in St. Charles is Sunday ($108). On the other hand, travelers can expect to pay the most on Saturday, when the average nightly price is $145.

How far ahead should you book a hotel in St. Charles?

Save money by booking a hotel at least 49 days before your trip to St. Charles. The lowest price found when booking 49 days ahead was $49 per night.

Cheapest hotels in St. Charles, Missouri

Discover affordable stays in St. Charles that provide a quality experience without breaking the bank. Hotels in St. Charles can be found for as low as $52 per night. There is currently one property in St. Charles that can be booked for this price. Woodspring Suites St Louis St Charles is one of the hotels that can be booked for the lowest price in St. Charles. Price data was last updated on 13 March 2026
These St. Charles properties charge the lowest price per night of those we've come across. If you have the flexibility, change the dates selected to compare prices.
2100 Old Hwy 94 S., St. Charles, MO, United States
4.5 km from city centre
Free Wi-Fi
Parking
$52
Avg. per night
3800 Harry South Truman Boulevard, St. Charles, MO, United States
5.9 km from city centre
Free Wi-Fi
Parking
$64
Avg. per night
1 Ameristar Boulevard, St. Charles, MO, United States
2.4 km from city centre
Free Wi-Fi
Parking
$70
Avg. per night
3040 West Clay Street, St. Charles, MO, United States
3.5 km from city centre
Pool
Free Wi-Fi
Parking
$75
Avg. per night
1310 Bass Pro Drive, St. Charles, MO, United States
1.9 km from city centre
Free Wi-Fi
$77
Avg. per night
150 Fountain Lakes Boulevard, St. Charles, MO, United States
4.7 km from city centre
Pool
Free Wi-Fi
Parking
$79
Avg. per night
1800 Zumbehl Road, St. Charles, MO, United States
3.0 km from city centre
Free Wi-Fi
Parking
$84
Avg. per night
32 Research Park Circle, St. Charles, MO, United States
18.5 km from city centre
Pool
$90
Avg. per night
1400 S. 5th Street, St. Charles, MO, United States
2.1 km from city centre
Pool
Free Wi-Fi
Parking
$100
Avg. per night
1425 South 5th Street, St. Charles, MO, United States
1.9 km from city centre
Pool
Airport shuttle
$106
Avg. per night
3720 West Clay Street, St. Charles, MO, United States
5.5 km from city centre
Pool
Free Wi-Fi
Parking
$115
Avg. per night
333 Camelback Road, St. Charles, MO, United States
2.6 km from city centre
Free Wi-Fi
Parking
$132
Avg. per night
3098 Elm Point Industrial Drive, St. Charles, MO, United States
3.7 km from city centre
Pool
Free Wi-Fi
Parking
$135
Avg. per night
2 Convention Center Plz, St. Charles, MO, United States
2.1 km from city centre
Pool
Free Wi-Fi
Parking
$137
Avg. per night

Other accommodations in St. Charles

Find the perfect hostel, theme hotel, or holiday rental for your stay in St. Charles.
1 Ameristar Boulevard, St. Charles, MO, United States
2.4 km from city centre
Free Wi-Fi
Parking
$70
Avg. per night
333 Camelback Road, St. Charles, MO, United States
2.6 km from city centre
Free Wi-Fi
Parking
$132
Avg. per night
1400 S. 5th Street, St. Charles, MO, United States
2.1 km from city centre
Pool
Free Wi-Fi
Parking
$100
Avg. per night
1190 South Main Street, St. Charles, MO, United States
2.0 km from city centre
Pool
Free Wi-Fi
Parking
$139
Avg. per night

Where to stay in St. Charles

Explore different neighbourhoods and areas within St. Charles to find the perfect location for your stay. Map data was last updated on 13 March 2026.
Whether you're visiting St. Charles for leisure or business, utilize the map to find hotels close to your ideal location. Users can click on a hotel's name to find more information about it, such as price, reviews, and amenities, and also find different deals for the property.

About St. Charles

Originally founded in 1769 as “Les Petites Côtes”, Saint Charles is a historically rich city that now forms part of St. Louis’ suburban sprawl. It was once a significant river port and played an important role in the westward expansion of the United States. During the 1920s, Saint Charles served as Missouri’s capital.

Things to do in St. Charles

Hugging the riverfront is the St. Charles Historic District, which preserves the site of the Missouri River’s first permanent European settlement. It was here that Lewis and Clark departed for their Corps of Discovery Expedition in 1804 and where the first state capitol in Missouri was built. Comprised of four connected brick buildings, the capitol houses recreated government meeting rooms filled with historic artefacts.

Replicas of the keelboat and pirogues used during the landmark 1804 exhibition are on display at the Lewis & Clark Boat House and Museum, which occupies a two-storey building overlooking the Missouri River. Browse the Native American artefacts on display in the second-floor exhibit and admire the largest indoor mural in the state, “Missouri River Walk”. Adjacent to the museum is Bishop’s Landing and a large sculpture depicting Lewis and Clark.

Changing exhibitions and concerts are showcased at the Foundry Art Centre, which also houses 20 studios where you can watch creative artists at work. It can easily be accessed along the Katy Trail, a 382-kilometre-long route that follows the northern bank of the Missouri River. In Saint Charles, it passes through Frontier Park with its picnic shelters and outdoor stage.

Getting around St. Charles

Saint Charles is around 30 minutes’ drive from St. Louis and 15 minutes from St. Louis Lambert International Airport, which has flights to destinations across North America. Regular buses connect to Saint Charles and travel throughout the city, connecting most of its attractions.

Facts about staying in St. Charles

Find useful tips and insights about staying in St. Charles to help you make the most of your experience. FAQs were last updated on 13 March 2026.
  • What are the best hotels in St. Charles?

    Ameristar Casino Resort Spa St. Charles is a very popular hotel in St. Charles, with a score of 8.0 from 302 reviews. Embassy Suites by Hilton St. Louis St. Charles (8.5 from 724 reviews) and Drury Plaza Hotel St. Louis St. Charles (9.2 from 911 reviews) are also highly rated St. Charles hotels based on recent feedback from HotelsCombined users.

  • What is a good hotel near Ameristar Casino St. Charles?

    Ameristar Casino Resort Spa St. Charles is a good hotel close to Ameristar Casino St. Charles - it has scored 8.0 over 302 reviews from HotelsCombined users.

  • What is a good hotel in St. Charles near St. Charles Convention Center?

    Ameristar Casino Resort Spa St. Charles is rated 8.0 from 302 reviews and is close to St. Charles Convention Center.

  • Is there a good hotel near St. Charles Historic District?

    If you’re looking for good hotels near St. Charles Historic District, consider Ameristar Casino Resort Spa St. Charles (rated 8.0 over 302 reviews).

  • Are there any hotels in St. Charles close to Lambert-St Louis?

    The closest hotel to Lambert-St Louis is Candlewood Suites St. Louis - St. Charles By IHG, which is located 3.0 km away from the city centre.

  • What are some other cities to stay in when visiting Missouri?

    In addition to St. Charles, travellers opt to visit University City when visiting Missouri. Kansas City is also a popular choice to visit.

  • How many hotels are there in St. Charles?

    In total, there are 116 hotels to choose from in St. Charles, compared to 13,908 properties in Missouri.

  • What are the most popular landmarks to visit in St. Charles?

    There’s so much to see and do in St. Charles, but we’ve found that the most popular landmarks are Ameristar Casino St. Charles, St. Charles Convention Center, and St. Charles Historic District. You’ll want to stay in St. Charles to visit Ameristar Casino St. Charles, St. Charles to visit St. Charles Convention Center, and St. Charles to visit St. Charles Historic District.

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Consider alternative stays in St. Charles

If you are looking for a specific type of hotel, consider these options for trips to St. Charles